[conspire] COVID at the end of 2021

[Les Faby]

J&J encodes the same full spike D614G variant with 2 proline substitutions
to encode the pre-fusion spike protein as the mRNA vaccines.

Reference:
How the Johnson & Johnson Vaccine Works https://nyti.ms/2WuvMsA

On Sat, Jan 1, 2022, 10:13 PM Rick Moen <rick at linuxmafia.com> wrote:

> Quoting Paul Zander (paulz at ieee.org):
>
> [snip that you had Pfizer and the Pfizer booster]
>
> > Now I am wondering if my next booster, whenever that is promoted,
> > should be J&J so as to add a different line of defense to the castle
> > model.
>
> Awfully good question.  I'll do you a favour and not give you a poorly
> informed guess based on quickly winging it.  ;->
>
> We're all amateur virologists/epidemilogists, at this point, trying to
> sort out a lot of ambivalent information and hoping to filter out the
> rubbish, and (I'm sure like you) I try to be super-careful, but one way
> to increase the chance of screwing up would be to overconfidently just
> Web-search a question and post what you find as the answer, without
> a good grounding in the subject.  And I'm going to be properly humble
> and say I just don't know enough.
>
> That having been said, if you want to see what the Wisdom of the Web has
> to say, Web-search "vaccine mixing".  You'll find a lot of stuff from
> reporters quoting seemingly credible medical authorities.  However, what
> you mostly find is medical authorities endorsing following up an initial
> J&J regime with one of the two mRNA boosters, on grounds of the latter
> not coding for the for the exact same part of the spike protein.
>
> Whether informed sources would recommend J&J as a 2nd booster after
> three Pfizer shots is unclear.  Complicating that calculation is the
> observed fact that the J&J vaccine has never generated as strong an
> immune response as the mRNA vaccines.
>
> If you trust your primary care physician's advice, asking him/her might
> be a reasonable thing to do.
>
> --
> Cheers,        "Public health is not private health.  Epidemics are not
> personal
> Rick Moen      diseases, and pandemics are not even national:  They take
> place
> rick at linuxmafia.com          across the shared immune system of human
> society."
> McQ! (4x80)                  -- Indi Samarajiva, https://t.co/bW2w059PYp
>
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