[conspire] When to get a covid test, brains, and a weird case, and a cardiology vs. immunology joke

[Ruben Safir]

On Wed, Aug 05, 2020 at 09:42:28PM -0700, Deirdre Saoirse Moen wrote:
> Note: I saved the article with the good joke for last. :P
> 
> Optimum time to get a nasal swab test (not the at home type, which is less accurate):
> 
> tl;dr: 2-4 days after first symptoms, see figure 2
> 
> https://www.acpjournals.org/doi/10.7326/M20-1495
> 
> 
> Truly depressing subject: structural brain changes in covid patients. Very technical neuroscience.
> 
> https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30228-5/fulltext
> 

Don't believe it.


> Study findings revealed possible disruption to micro-structural and functional brain integrity in the recovery stages of COVID-19, suggesting the long-term consequences of SARS-CoV-2. (In *most* of the people.)
> 
> 
> For the truly horrifying one-off, though:
> 
> https://www.medrxiv.org/content/10.1101/2020.07.23.20160770v1
> 
> Autoimmune Encephalitis Presenting with Acute Excited Catatonia in a 40-Year-Old Male Patient with Covid-19
> 
> > We are not aware of other types of encephalitis with such distinct pyramidal tract symptoms and raise the possibility that this may be a novel form of autoimmune encephalitis induced by infection with SARS-CoV-2.
> 
> (pyramidal tract being motor control systems, encephalitis is inflammation of at least part of the brain; in this case, several parts were involved)
> 
> 
> And, for the lightest piece, the Atlantic piece, which opens with a funny cardiologist vs. immunologist joke:
> 
> https://www.theatlantic.com/health/archive/2020/08/covid-19-immunity-is-the-pandemics-central-mystery/614956/
> 
> I had noticed this in papers and wondered if I’d missed something, so glad to know I didn’t:
> 
> > Normally, the immune system mobilizes different groups of cells and molecules when fighting three broad groups of pathogens: viruses and microbes that invade cells, bacteria and fungi that stay outside cells, and parasitic worms. Only the first of these programs should activate during a viral infection. But Iwasaki’s team recently showed that all three activate in severe COVID-19 cases. “It seems completely random,” she says. In the worst cases, “the immune system almost seems confused as to what it’s supposed to be making.”
> 
> 
> Also, it links to a piece about the long haulers, of which I am one. Still symptomatic after 6-1/2 months. :(
> 
> https://www.theatlantic.com/health/archive/2020/06/covid-19-coronavirus-longterm-symptoms-months/612679/
> 
> Wound up in the ER 2-1/2 weeks ago with a high heart rate and put on a heart monitor. :O Ever since covid, I’ve had an occasional random high heart rate. Waiting to hear back what the results are and so forth. But…yeah, this disease sucks.
> 
> Deirdre
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