<html><head><meta http-equiv="Content-Type" content="text/html; charset=utf-8"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class="">1. Based on autopsies performed, fwiw. Cells most involved were astrocytes, which form brain structure and help endothelial cells form the blood/brain barrier.<div class=""><br class=""></div><div class=""><a href="https://www.medrxiv.org/content/10.1101/2020.10.09.20207464v1" class="">https://www.medrxiv.org/content/10.1101/2020.10.09.20207464v1</a></div><div class=""><br class=""></div><div class=""><a href="https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(20)30495-1" class="">https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(20)30495-1</a></div><div class=""><br class=""></div><div class=""><br class=""></div><div class="">2. HIV news: one of the mysteries in HIV was how the virus got into the nucleus. The port in the nucleus is 40nm, and the capsid is 60nm. For a long time, it was assumed that the virus shed the outer capsid prior to nuclear entry.</div><div class=""><br class=""></div><div class="">Spoiler alert: it does not.</div><div class=""><br class=""></div><div class="">I immediately thought of the videos of octopuses and bottles, e.g., this one: <a href="https://www.youtube.com/watch?v=DT97tS_XeaU" class="">https://www.youtube.com/watch?v=DT97tS_XeaU</a></div><div class=""><br class=""></div><div class="">Or: this octopus through a hole: <a href="https://www.youtube.com/watch?v=E3N0i_KM8cI" class="">https://www.youtube.com/watch?v=E3N0i_KM8cI</a></div><div class=""><br class=""></div><div class="">Anyhow, here’s the paper from Yale:</div><div class=""><br class=""></div><div class=""><a href="https://www.biorxiv.org/content/10.1101/2020.08.10.245522v1.full.pdf" class="">https://www.biorxiv.org/content/10.1101/2020.08.10.245522v1.full.pdf</a></div><div class=""><br class=""></div><div class="">I love that Buckminster Fuller is referenced indirectly:</div><div class=""><br class=""></div><div class=""><blockquote type="cite" class="">HIV-1 capsid is composed of capsomeres of approximately 250 capsid protein (CA) hexamers and 12 CA pentamers, which assemble into a fullerene cone….</blockquote></div><div class=""><br class=""></div><div class="">Deirdre</div></body></html>